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New Priorclave 400L Front Loading Steam Autoclave
Product code: NPF400L
Priorclave autoclaves offer an unparalleled 36-month parts and labor warranty, and a 20-year pressure vessel warranty.
When You Absolutely, Positively, Must Kill Every Pathogen in the Sample, Accept No Substitutes.
The Priorclave 400L is a front-loading laboratory autoclave with a cylindrical 316L stainless steel chamber and burnished 316L door, engineered for efficient high-pressure sterilization. Operating up to 277°F (136°C) at 32 psi (2.2 Bar), it supports electrically generated steam or a house steam source.
The Tactrol® 2 Control System enables automated cycles, electronic cycle logging via USB, and advanced safety features. Modular design allows easy upgrades as lab requirements evolve, while anti-tip shelving and Biomaster® antimicrobial surfaces reduce contamination risks. ASME stamped and ETL listed, the unit is built for long-term reliability and regulatory compliance.
The advantages inherent in using a cylindrical-vessel sterilizer become especially apparent with large-volume front-loading autoclaves. By eliminating corners, the cylindrical vessel improves steam circulation, preventing cold pockets and assuring complete sterilization without excessive cycle times. If you aren’t processing flat trays of medical instruments on a daily basis, then you neither need nor want a rectangular-chamber autoclave.
There are also impressive cost-savings associated with moving to a cylindrical-vessel sterilizer. A lower part count, more efficient steam generation, and lighter-gauge pressure vessel don’t just reduce the purchase price, they drastically reduce maintenance and utility costs: On an annual basis, a cylindrical-vessel front-loading autoclave can be expected to use 75% less energy and 87% less water than a comparable “energy/water saving” rectangular model.
Every Priorclave front-loading sterilizer comes outfitted with an advanced Tactrol control system. These industry-favored control systems are optimized for research, offering exceptional cycle customization: One-touch operation, delayed cycle start, media warming, automatic cycle repeat, and more.
Features:
- Front-loading, cylindrical 316L stainless steel chamber
- Diameter: 24.8” (630 mm)
- Depth: 45.3” (1150 mm)
- Burnished 316L stainless steel door
- Operating range: Up to 277°F (136°C) / 32 psi (2.2 Bar)
- Steam source: Internal electric OR house steam
- Tactrol® 2 Control System
- Electronic cycle logging via USB
- Modular design / upgradable
- Anti-tip loading shelves
- Biomaster® antimicrobial surfaces
- Quickseal 2 door with Permission-Based Door Release, thermal & pressure locks
- Redundant Safety Gate
- Pressure Safety Valve: 2.5 Bar / 36.3 psi
- Thermal cut out: 150°C / 302°F
- Non-tip shelves
- ASME stamped, ETL listed, CE Marked
Priorclave sterilizers are built in the UK to a modular design enabling easy upgrading during their working life as your requirements change. Every steam heated Priorclave is fitted with a Thermostatic Air Purge Valve and an electrically operated Vent Valve. All pipe to pipe joints are brazed with compression joints to specific components (stainless pipework is available). Priorclave autoclaves offer a 36-month limited parts and labor warranty, 20-year pressure vessel warranty, and unlimited technical support.
Safety
At Priorclave, the safety of your staff and students comes first. Our Quickseal 2 door, with Permission-based Door Release, is fitted with thermal and pressure locks to prevent opening at load temperatures above 80°C (176°F) and pressures above 0.2 Bar (2.9 psi) (as per BS 2646). The door is also fitted with a Redundant Safety Gate, so that any residual pressure can safely escape before the door can move freely (in accordance with the UK Health and Safety Executive’s note PM73). All units come with a Pressure Safety Valve set to 2.5 Bar (36.3 psi) and a 150°C (302°F) thermal cut out (per BS 6759); selected external panels and surfaces are thermally insulated. All front loading models have non-tip shelves.
Priorclave is the only manufacturer offering the same fully featured programmable control system on every model, from the smallest laboratory benchtop sterilizer to the largest industrial pass-through unit. The Tactrol 2 system puts every operating parameter within your control, with no re-training required as you move from one unit to another. Using our Tactrol 2 Control System, operators can limit user access to specific pre-programmed, validated cycles, via fail-safe one-button start or key switch activation. Program modifications are likewise key switch or password protected.
Options:
- Tactrol 5 Program Memory
- Tactrol 10 Program Memory
- Upgrade Tactrol 5 to Tactrol 10 Program Memory
- Tactrol Self-Monitoring System
- Tactrol Plain-Paper Printer
- Setting Lock Key Switch (standard with any Tactrol memory unit)
- Pulsed Free Steaming
- Load Sensed Process Timing
- Automatic Water Fill System (models with in-chamber steam generation only)
- Water Softener
- Purified Water Level Sensor (models with in-chamber steam generation only)
- Stainless Steel Pipework
- Clean Steam Generation
- Air Intake Filter System
- Exhaust Filtration System
- Air Ballast System for Accelerated Liquid Cooling (with or without external air supply)
- Load Temperature Monitor
- Chamber Pressure Monitor
- Armored Wandering Probe
- External USB Port (included in North American models)
- Combined Pre-Cycle Vacuum & Vacuum Cooling
- Post-Cycle Vacuum Drying
- Automatic Cycle Repeat
- Stainless Steel Loading Basket
- Stainless Steel Waste Container
- Loading Hoist
- Drain Condenser
- Two-Year Spares Kit
- Three-Year Spares Kit
- IQ/OQ/PQ Documentation
Read More about Priorclave here
WARRANTY:
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36-month limited parts and labor warranty
- 20-year pressure vessel warranty
- Unlimited technical support
Technical Specifications
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Working Volume: 400 Liters
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Operating Range: Up to 277°F (136°C), 32 psi (2.2 Bar)
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Chamber Dimensions: 24.8" diameter x 45.3" deep (630mm x 1150mm)
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Chamber Material: Brushed grade 316L stainless steel
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Heat Input: 17.9kW (internal electric) OR 1.2kW (house steam, three-phase)
Side‑by‑side comparison table for the Priorclave 320L vs 400L front-loading
| Feature / Spec |
Priorclave 320L |
Priorclave 400L |
| Working Volume |
320 Liters |
400 Liters |
| Chamber Depth |
40.2” (1020 mm) |
45.3” (1150 mm) |
| Chamber Diameter |
~24.8” (630 mm) |
24.8” (630 mm) |
| Door Material |
Burnished 316L stainless steel |
Burnished 316L stainless steel |
| Chamber Material |
Brushed 316L stainless steel |
Brushed 316L stainless steel |
| Operating Range |
Up to 277 °F / 32 psi (136 °C / 2.2 Bar) |
Up to 277 °F / 32 psi (136 °C / 2.2 Bar) |
| Steam Source |
Internal electric OR house steam |
Internal electric OR house steam |
| Weight (Unloaded) |
~660 lbs (300 kg) |
~1,000 lbs (590 kg) |
| External Footprint |
Smaller, compact installation |
Larger installation footprint |
| Standard Features |
Tactrol® Control System, Quickseal safety door, Electronic cycle logging, Assisted load cooling, Media warming, Anti-tip shelves, Biomaster® surfaces |
Tactrol® 2 Control System, Quickseal 2 safety door, Electronic cycle logging via USB, Assisted load cooling, Media warming, Anti-tip shelves, Biomaster® surfaces |
| Applications |
Research labs, education, life sciences, QA, moderate load sterilization |
Research labs, education, life sciences, QA, pharmaceutical, industrial, bulk/large load sterilization |
| Certifications |
ASME stamped, ETL listed, CE Marked |
ASME stamped, ETL listed, CE Marked |
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Features
Q: What is the working volume of the Priorclave 400L autoclave?
A: The Priorclave 400L has a working volume of 400 liters (approximately 105.7 US gallons), with internal chamber dimensions of 24.8” diameter x 45.3” deep.
Q: What temperatures and pressures can the Priorclave 400L reach?
A: It operates up to 277°F (136°C) at 32 psi (2.2 Bar) for effective steam sterilization.
Q: What materials are used in the chamber and door of the Priorclave 400L?
A: Both the chamber and door are manufactured from high‑grade 316L stainless steel; the chamber is brushed and the door is burnished.
Q: What control system does the Priorclave 400L use?
A: It uses the Tactrol® 2 Control System, which provides programmable cycles, one‑button start, delayed start, media warming, and electronic logging through a USB port.
Q: Does the Priorclave 400L include safety features?
A: Yes. It features the Quickseal 2 door with thermal and pressure locks, a Redundant Safety Gate, a Pressure Safety Valve set to 2.5 Bar (36.3 psi), and a thermal cut‑out at 150°C (302°F).
Q: What steam source options are available for the Priorclave 400L?
A: The unit can be supplied with internally generated electric steam or connected to a house steam source.
Q: Is the Priorclave 400L suitable for upgrading if requirements change?
A: Yes. It’s designed with a modular build to support upgrades as laboratory needs evolve.
Q: Can the Priorclave 400L log sterilization cycle data?
A: Yes. It has electronic cycle logging, with a USB port for exporting temperature, pressure, and timing data.
Q: Does the Priorclave 400L autoclave include assisted cooling features?
A: Yes. Assisted load cooling and media warming options are available as part of the standard feature set.
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